Regeneration-associated WNT Signaling Is Activated in Long-term Reconstituting AC133bright Acute Myeloid Leukemia Cells

Regeneration-associated WNT Signaling Is Activated in Long-term Reconstituting AC133bright Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized by two molecularly distinct self-renewing leukemic stem cell (LSC) populations most closely related to normal progenitors and organized as a hierarchy. A requirement for WNT/β-catenin signaling in the pathogen...

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Bibliographic Details
Main Authors: Alessandro Beghini, Francesca Corlazzoli, Luca Del Giacco, Matteo Re, Francesca Lazzaroni, Matteo Brioschi, Giorgio Valentini, Fulvia Ferrazzi, Anna Ghilardi, Marco Righi, Mauro Turrini, Marco Mignardi, Clara Cesana, Vincenzo Bronte, Mats Nilsson, Enrica Morra, Roberto Cairoli
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800595

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http://www.sciencedirect.com/science/article/pii/S1476558612800595

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