<b>Toxicity of the goji berry fruit associated with artificial excipients and dried without additives

• Main Authors: Débora Dayane Araújo de Moura, Cleidiane Josefa dos Santos Veloso, Valtânia Ana de Oliveira, Maria Eduarda Sousa e Silva, Ana Paula Peron
• Format: Article
• Language: English
• Published: Universidade Estadual de Maringá 2018-07-01
• Series: Acta Scientiarum : Biological Sciences
• Subjects: lycium barbarum l.; natural pharmaceutical product; cytotoxicity; genotoxicity; meristematic tissue.
• Online Access: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/37844

The aim of this study was to evaluate the cytotoxic and genotoxic potential of goji berry fruit-based pharmaceutical powders obtained from three pharmaceutical laboratories. The product A was tested at concentrations of 0.012; 0.025 and 0.05 g mL-1, and B and C at concentrations 0.02; 0.04 and 0.08 g mL-1. It was also evaluated the tea of the dried goji berry fruit (non-additives) in the concentrations 0.035; 0.07 and 0.14 g mL-1 for comparison to the results obtained with powdered goji berry. Tea concentrations in the two exposure times did not cause inhibition of cell division nor cellular alterations to meristem tissues. For the industrialized goji products, all concentrations analyzed caused significant antiproliferative effect to the tissues evaluated at the shortest time of analysis. There were no significant cellular changes in tissues exposed to industrialized goji. Therefore, under the conditions of analysis, goji berry powder, at the three concentrations evaluated, was cytotoxic to root meristems.