Reduction of inflammation and T cell activation after 6 months of cART initiation during acute, but not in early chronic HIV-1 infection

Reduction of inflammation and T cell activation after 6 months of cART initiation during acute, but not in early chronic HIV-1 infection

Abstract Objectives To investigate the impact of early combined antiretroviral therapy (cART) on inflammation biomarkers and immune activation during acute and early chronic HIV-1 infection. Methods We included 12 acute (AHI), 11 early chronic (EcHI), and 18 late chronic HIV-1-infected (LcHI) indivi...

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Bibliographic Details
Main Authors: Hury Hellen Souza de Paula, Ana Cristina Garcia Ferreira, Diogo Gama Caetano, Edson Delatorre, Sylvia Lopes Maia Teixeira, Lara Esteves Coelho, Eduarda Grinsztejn João, Michelle Morata de Andrade, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdilea Gonçalves Veloso, Mariza Gonçalves Morgado, Monick Lindenmeyer Guimarães, Fernanda Heloise Côrtes
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Retrovirology
Subjects:
HIV-1 acute infection
Inflammation
cART
Immune activation
IP-10
IL-18
Online Access:http://link.springer.com/article/10.1186/s12977-018-0458-6

Internet

http://link.springer.com/article/10.1186/s12977-018-0458-6

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