Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1‐WNT2/HGF signaling pathway

Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1‐WNT2/HGF signaling pathway

Abstract Background The human liver possesses a remarkable capacity for self‐repair. However, liver fibrosis remains a serious medical concern, potentially progressing to end‐stage liver cirrhosis and even death. Liver fibrosis is characterized by excess accumulation of extracellular matrix in respo...

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Bibliographic Details
Main Authors: Xi Dong, Yun Luo, Shan Lu, Han Ma, Wenchao Zhang, Yue Zhu, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Clinical and Translational Medicine
Subjects:
ID1
HGF
WNT2
regeneration
ursodesoxycholic acid
liver fibrosis
Online Access:https://doi.org/10.1002/ctm2.296

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