ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells

ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells

Abstract Background Kruppel family member zinc binding protein 89 (ZBP-89), also known as ZNF148, regulates Bak expression via binding to GC-rich promoter domain. It is not clear if other GC-rich binding factors, such as Sp family members, can interact with ZBPp-89 on Bak expression. This study aims...

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Bibliographic Details
Main Authors: Xia Kong, Pin Xu, Wei-Jie Cai, Huai-Gao Wang, Bin-Bin Li, Guo-Liang Huang, Zhi-Wei He, George Chen, Cai-Guo Ye
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Sp1
Sp3
ZBP-89
Bak
Hepatocellular carcinoma
Online Access:http://link.springer.com/article/10.1186/s12885-018-4349-y

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