Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells
cAMP response element binding protein (CREB)-regulated transcription coactivator 2 (CRTC2), a member of the novel CRTC family of transcriptional coactivators that activates basic leucine zipper transcription factors, including CREB, is overexpressed in many carcinomas, including colon cancer. Phosph...
Main Authors: | Yi Wang MD, Qian Liu MD, Hanshuo Zhang PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-09-01
|
Series: | Technology in Cancer Research & Treatment |
Online Access: | https://doi.org/10.1177/1533033820962111 |
Similar Items
-
Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment
by: Tim Sonntag, et al.
Published: (2019-01-01) -
The CREB Coactivator CRTC2 Is a Lymphoma Tumor Suppressor that Preserves Genome Integrity through Transcription of DNA Mismatch Repair Genes
by: Minggang Fang, et al.
Published: (2015-06-01) -
Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer
by: Amelio, A.L, et al.
Published: (2022) -
A role for the CREB coactivator CRTC2 in the hypothalamic mechanisms linking nutrient sensing with the regulation of gene expression and energy homeo stasis
by: Lerner, Robin
Published: (2010) -
The Essential Role of the Crtc2-CREB Pathway in β Cell Function and Survival
by: Eberhard, Chandra
Published: (2013)