Modernization of Enoxaparin Molecular Weight Determination Using Homogeneous Standards

Modernization of Enoxaparin Molecular Weight Determination Using Homogeneous Standards

Enoxaparin is a low-molecular weight heparin used to treat thrombotic disorders. Following the fatal contamination of the heparin supply chain in 2007–2008, the U.S. Pharmacopeia (USP) and U.S. Food and Drug Administration (FDA) have worked extensively to modernize the unfractionated heparin and eno...

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Bibliographic Details
Main Authors: Katelyn M. Arnold, Stephen J. Capuzzi, Yongmei Xu, Eugene N. Muratov, Kevin Carrick, Anita Y. Szajek, Alexander Tropsha, Jian Liu
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Pharmaceuticals
Subjects:
enoxaparin
USP
MW determination
oligosaccharide calibrants
computational modeling
HPLC
compendial test
Online Access:https://www.mdpi.com/1424-8247/10/3/66

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https://www.mdpi.com/1424-8247/10/3/66

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