Study of chronic effect of Losartan in inhibition of kidney glomerular number and glomerular volume changes in uninephrectomized diabetic rats(Stereological study).

Background: Diabetic nephropathy is one of the cause of the end stage of renal disease (ESRD). Hyperglicemia activate intrarenal Renin-Angiotensin system and highly AngiotensinII is produced locally in glomeruli. In this research AT1(Angiotensin type 1) receptors blocked by Losartan and effects of t...

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Bibliographic Details
Main Authors: majid Tavafi, abdolahman Dezfulian, mohammad hadi Kochek, hayat Mombeini, asadollah Tavakoli, mohammad javad Tarahi
Format: Article
Language:fas
Published: Lorestan University of Medical Science 2005-02-01
Series:Yafteh
Subjects:
Online Access:http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-249&slc_lang=en&sid=1