A critical role for glycine transporters in hyperexcitability disorders

A critical role for glycine transporters in hyperexcitability disorders

Defects in mammalian glycinergic neurotransmission result in a complex motor disorder characterized by neonatal hypertonia and an exaggerated startle refl ex, known as hyperekplexia (OMIM 149400). This affects newborn children and is characterized by noise or touch-induced seizures that result in mu...

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Bibliographic Details
Main Authors:	Robert J Harvey, Eloisa Carta, Brian R Pearce, Seo-Kyung Chung, Stéphane Supplisson, Mark I Rees, Kirsten Harvey
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2008-03-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	Startle disease VIAAT glycine encephalopathy Glycine transporters GlyT1 GlyT2
Online Access:	http://journal.frontiersin.org/Journal/10.3389/neuro.02.001.2008/full

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