Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine

Mantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified appr...

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Main Authors: Jose D. Sandoval-Sus, Eduardo M. Sotomayor, Bijal D. Shah
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387617300328
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spelling doaj-4e2756f5ac8546f395a69bbb69aed33b2020-11-25T00:20:48ZengElsevierHematology/Oncology and Stem Cell Therapy1658-38762017-09-0110399115Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized MedicineJose D. Sandoval-Sus0Eduardo M. Sotomayor1Bijal D. Shah2Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA; Corresponding author at: H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA.Department of Hematology/Oncology, George Washington University, Washington, D.C., USADepartment of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USAMantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified approaches. In the following review we provide a therapeutic roadmap to strategically guide treatment for newly diagnosed and relapsed/refractory patients highlighting pivotal and recently published results involving known and novel therapies. Keywords: Mantle cell lymphoma, Prognosis, Treatmenthttp://www.sciencedirect.com/science/article/pii/S1658387617300328
collection DOAJ
language English
format Article
sources DOAJ
author Jose D. Sandoval-Sus
Eduardo M. Sotomayor
Bijal D. Shah
spellingShingle Jose D. Sandoval-Sus
Eduardo M. Sotomayor
Bijal D. Shah
Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
Hematology/Oncology and Stem Cell Therapy
author_facet Jose D. Sandoval-Sus
Eduardo M. Sotomayor
Bijal D. Shah
author_sort Jose D. Sandoval-Sus
title Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
title_short Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
title_full Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
title_fullStr Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
title_full_unstemmed Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine
title_sort mantle cell lymphoma: contemporary diagnostic and treatment perspectives in the age of personalized medicine
publisher Elsevier
series Hematology/Oncology and Stem Cell Therapy
issn 1658-3876
publishDate 2017-09-01
description Mantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified approaches. In the following review we provide a therapeutic roadmap to strategically guide treatment for newly diagnosed and relapsed/refractory patients highlighting pivotal and recently published results involving known and novel therapies. Keywords: Mantle cell lymphoma, Prognosis, Treatment
url http://www.sciencedirect.com/science/article/pii/S1658387617300328
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AT bijaldshah mantlecelllymphomacontemporarydiagnosticandtreatmentperspectivesintheageofpersonalizedmedicine
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