Evaluation of Low Molecular Weight Cross Linked Chitosan Nanoparticles, to Enhance the Bioavailability of 5-Flourouracil
The present study aimed to formulate 5-fluorouracil loaded cross linked chitosan nanoparticles based on chemical cross-linking of low molecular weight chitosan with glutaraldehyde by reverse micelles technique as 5-FU is less hydrophobic, relatively potent, has a shorter half-life, is rapidly metabo...
Main Authors: | Aisha Sethi, Mahmood Ahmad, Tayyaba Huma, Ikrima Khalid, Imtiaz Ahmad |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-07-01
|
Series: | Dose-Response |
Online Access: | https://doi.org/10.1177/15593258211025353 |
Similar Items
-
Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity
by: Aisha Sethi, et al.
Published: (2021-01-01) -
Comparative efficacy of 5flourouracil/calcium leucovorine versus 5flourouracil/calcium leucovorine plus oxaliplatin in the adjuvant treatment of colonic carcinoma in Kashmir
by: Hamid Deva Shaiq, et al.
Published: (2013-01-01) -
Gemcitabine/5-flourouracil/leucovorin for the treatment of advanced pancreatic carcinoma
by: Reza Malayeri, et al.
Published: (2008-10-01) -
Resveratrol abrogates 5-flourouracil -induced hepatotoxicity: A preclinical study
by: Elias Adikwu, et al.
Published: (2020-12-01) -
Effect of 5-Flourouracil On HCT-116 P53+/- Human Colon Cancer Cells
by: Perwaiz, Sunela
Published: (2011)