Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy.

Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy.

The use of antibiotics targeting the obligate bacterial endosymbiont Wolbachia of filarial parasites has been validated as an approach for controlling filarial infection in animals and humans. Availability of genomic sequences for the Wolbachia (wBm) present in the human filarial parasite Brugia mal...

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Bibliographic Details
Main Authors: Zhiru Li, Amanda L Garner, Christian Gloeckner, Kim D Janda, Clotilde K Carlow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3226453?pdf=render

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