Predicting the evolution of antibiotic resistance
<p>Abstract</p> <p>Mutations causing antibiotic resistance are often associated with a cost in the absence of antibiotics. Surprisingly, a new study found that bacteria adapting to increased temperature became resistant to rifampicin. By studying the consequences of the involved mu...
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| Format: | Article |
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BMC
2013-02-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/11/14 |
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doaj-4e0699071f4546e8b3fa27f3af173f652020-11-24T20:54:14ZengBMCBMC Biology1741-70072013-02-011111410.1186/1741-7007-11-14Predicting the evolution of antibiotic resistanceSchenk Martijn Fde Visser J Arjan GM<p>Abstract</p> <p>Mutations causing antibiotic resistance are often associated with a cost in the absence of antibiotics. Surprisingly, a new study found that bacteria adapting to increased temperature became resistant to rifampicin. By studying the consequences of the involved mutations in different conditions and genetic backgrounds, the authors illustrate how knowledge of two fundamental genetic properties, pleiotropy and epistasis, may help to predict the evolution of antibiotic resistance.</p> <p>See research article <url>http://www.biomedcentral.com/1471-2148/13/50</url></p> http://www.biomedcentral.com/1741-7007/11/14 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Schenk Martijn F de Visser J Arjan GM |
| spellingShingle |
Schenk Martijn F de Visser J Arjan GM Predicting the evolution of antibiotic resistance BMC Biology |
| author_facet |
Schenk Martijn F de Visser J Arjan GM |
| author_sort |
Schenk Martijn F |
| title |
Predicting the evolution of antibiotic resistance |
| title_short |
Predicting the evolution of antibiotic resistance |
| title_full |
Predicting the evolution of antibiotic resistance |
| title_fullStr |
Predicting the evolution of antibiotic resistance |
| title_full_unstemmed |
Predicting the evolution of antibiotic resistance |
| title_sort |
predicting the evolution of antibiotic resistance |
| publisher |
BMC |
| series |
BMC Biology |
| issn |
1741-7007 |
| publishDate |
2013-02-01 |
| description |
<p>Abstract</p> <p>Mutations causing antibiotic resistance are often associated with a cost in the absence of antibiotics. Surprisingly, a new study found that bacteria adapting to increased temperature became resistant to rifampicin. By studying the consequences of the involved mutations in different conditions and genetic backgrounds, the authors illustrate how knowledge of two fundamental genetic properties, pleiotropy and epistasis, may help to predict the evolution of antibiotic resistance.</p> <p>See research article <url>http://www.biomedcentral.com/1471-2148/13/50</url></p> |
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http://www.biomedcentral.com/1741-7007/11/14 |
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