Restoration of mRNA Expression of Solute Carrier Proteins in Liver of Diet-Induced Obese Mice by Metformin

Restoration of mRNA Expression of Solute Carrier Proteins in Liver of Diet-Induced Obese Mice by Metformin

Metformin (MET), the most common medicine for type 2 diabetes (T2DM), improves insulin sensitivity by targeting the liver, intestine and other organs. Its impact on expression of the solute carrier (Slc) transporter genes have not been reported in the mechanism of insulin sensitization. In this stud...

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Bibliographic Details
Main Authors: Jiamei Le, Yi Fu, Qiuqin Han, Xindong Wei, Houlin Ji, Yifan Chen, Qiuying Wang, Peixian Pi, Jilei Li, Xinjie Lin, Xiaoying Zhang, Yong Zhang, Jianping Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
metformin
transcriptome
solute carrier transporter
insulin sensitivity
obesity
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.720784/full

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