Progressive Increase in Telomerase Activity From Benign Melanocytic Conditions to Malignant Melanoma

Progressive Increase in Telomerase Activity From Benign Melanocytic Conditions to Malignant Melanoma

The expression of telomerase activity and the in situ localization of the human telomerase RNA component (hTR) in melanocytic skin lesions was evaluated in specimens from sixty-three patients. Specimens of melanocytic nevi, primary melanomas and subcutaneous metastases of melanoma were obtained fro...

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Bibliographic Details
Main Authors: Ruben D. Ramirez, Stefania D'Atri, Elena Pagani, Tullio Faraggiana, Pedro Miguel Lacal, R. Stan Taylor, Jerry W. Shay
Format: Article
Language:English
Published: Elsevier 1999-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
skin cancer
immortality
telomeres
metastases
prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800347

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