Health technology assessment of hyaluronans in osteoarthritis treatment

• Main Authors: A. S. Kolbin, I. A. Vilum, Yu. E. Balykina, M. A. Proskurin
• Format: Article
• Language: Russian
• Published: Izdatelstvo OKI 2018-06-01
• Series: Качественная клиническая практика
• Subjects: health technology assessment; osteoarthrosis; osteoarthritis; hyaluronans; pharmacoeconomics; budget impact analysis; synvisk
• Online Access: https://www.clinvest.ru/jour/article/view/195

Health technology assessment has been performed for osteoarthritis treatment. Several technologies were evaluated — NSAIDs, steroid therapy and hyaluronans viscosupplementation for inter joint injection. Expertise based on literature data and modeling evaluated outcomes during 2.5 years in the fourth stage of illness including knee replacement. Only one strategy — with Synvisk® injection has been eff ective in the endpoint of modeling. Expenditures for NSAIDs, steroids and Synvisk® were calculated. Synvisk® usage is more preferable based on budget impact analysis. Th is strategy can save no less than 81 million RUR (on 1000 pts.). Saved money can cover an additional quantity of patients for Synvisk® treatment. Synvisk® technology is delay a necessity of knee replacement surgeon in patients with fourth stage of osteoarthritis following to budget economy during 6-12 months treatment already.