AMD3100 inhibits the migration and differentiation of neural stem cells after spinal cord injury

Abstract It was reported that CXCR4 signaling played an important role in the migration and differentiation of endogenous neural stem cells after spinal cord injury (SCI). However, the molecular mechanism of it is still unclear. Here, we established a model of SCI in rats and AMD3100 was used to tre...

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Bibliographic Details
Main Authors: Jia-Ming Liu, Kai Zhao, Liu-Xue Du, Yang Zhou, Xin-Hua Long, Xuan-Yin Chen, Zhi-Li Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00141-8