Structural, Mechanistic, and Functional Insights into an <i>Arthrobacter nicotinovorans</i> Molybdenum Hydroxylase Involved in Nicotine Degradation

Structural, Mechanistic, and Functional Insights into an <i>Arthrobacter nicotinovorans</i> Molybdenum Hydroxylase Involved in Nicotine Degradation

<i>Arthrobacter nicotinovorans</i> decomposes nicotine through the pyridine pathway. 6-hydroxypseudooxynicotine 2-oxidoreductase (also named ketone dehydrogenase, Kdh) is an important enzyme in nicotine degradation pathway of <i>A. nicotinovorans</i>, and is responsible for t...

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Bibliographic Details
Main Authors: Lei Wang, Xia Mu, Wenjin Li, Qin Xu, Ping Xu, Liyun Zhang, Yuebin Zhang, Geng Wu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
nicotine degradation
ketone dehydrogenase
Kdh
molybdenum hydroxylase
crystal structure
reaction mechanism
Online Access:https://www.mdpi.com/1420-3049/26/14/4387

Internet

https://www.mdpi.com/1420-3049/26/14/4387

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