Impact of dimensionality and network disruption on microrheology of cancer cells in 3D environments.

Dimensionality is a fundamental component that can have profound implications on the characteristics of physical systems. In cell biology, however, the majority of studies on cell physical properties, from rheology to force generation to migration, have been performed on 2D substrates, and it is not...

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Bibliographic Details
Main Authors: Michael Mak, Roger D Kamm, Muhammad H Zaman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4238946?pdf=render