Ellagic Acid Reduces High Glucose-Induced Vascular Oxidative Stress Through ERK1/2/NOX4 Signaling Pathway

Ellagic Acid Reduces High Glucose-Induced Vascular Oxidative Stress Through ERK1/2/NOX4 Signaling Pathway

Background/Aims: Elevated production of reactive oxygen species (ROS) is linked to endothelial dysfunction and is one of the key contributors to the pathogenesis of diabetic vascular complications. Emerging evidence has indicated that ellagic acid (EA), a polyphenol found in fruits and nuts, possess...

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Bibliographic Details
Main Authors: Artur Rozentsvit, Kevin Vinokur, Sherin Samuel, Ying Li, A. Martin Gerdes, Maria Alicia Carrillo-Sepulveda
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ellagic acid
Antioxidant
High glucose
Endothelial dysfunction
Endothelial cell
NOX4
ERK1/2
Diabetes
Online Access:https://www.karger.com/Article/FullText/485448

Internet

https://www.karger.com/Article/FullText/485448

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