A SAP domain-containing protein shuttles between the nucleus and cell membranes and plays a role in adhesion and migration in D. discoideum

Summary The AmpA protein reduces cell adhesion, thereby influencing cell migration in Dictyostelium. To understand how ampA influences cell migration, second site suppressors of an AmpA overexpressing cell line were created by REMI mutagenesis. Mutant candidates were identified by their ability to s...

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Bibliographic Details
Main Authors: Jessica S. Kelsey, Daphne D. Blumberg
Format: Article
Language:English
Published: The Company of Biologists 2013-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/4/396