Mining of Self-Organizing Map Gene-Expression Portraits Reveals Prognostic Stratification of HPV-Positive Head and Neck Squamous Cell Carcinoma

Mining of Self-Organizing Map Gene-Expression Portraits Reveals Prognostic Stratification of HPV-Positive Head and Neck Squamous Cell Carcinoma

Patients (pts) with head and neck squamous cell carcinoma (HNSCC) have different epidemiologic, clinical, and outcome behaviors in relation to human papillomavirus (HPV) infection status, with HPV-positive patients having a 70% reduction in their risk of death. Little is known about the molecular he...

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Bibliographic Details
Main Authors: Laura D. Locati, Mara S. Serafini, Maria F. Iannò, Andrea Carenzo, Ester Orlandi, Carlo Resteghini, Stefano Cavalieri, Paolo Bossi, Silvana Canevari, Lisa Licitra, Loris De Cecco
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
self-organizing map
head and neck cancer
treatment de-escalation
HP
molecular subtypes
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/11/8/1057

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