TLR-dependent control of Francisella tularensis infection and host inflammatory responses.

BACKGROUND:Francisella tularensis is the causative agent of tularemia and is classified as a Category A select agent. Recent studies have implicated TLR2 as a critical element in the host protective response to F. tularensis infection, but questions remain about whether TLR2 signaling dominates the...

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Bibliographic Details
Main Authors: Allison L Abplanalp, Ian R Morris, Bijaya K Parida, Judy M Teale, Michael T Berton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775407?pdf=render