St. John’s Wort Suppresses Growth in Triple-Negative Breast Cancer Cell Line MDA-MB-231 by Inducing Prodeath Autophagy and Apoptosis

St. John’s Wort Suppresses Growth in Triple-Negative Breast Cancer Cell Line MDA-MB-231 by Inducing Prodeath Autophagy and Apoptosis

The rational regulation of programmed cell death by means of autophagy and apoptosis has been considered a potential treatment strategy for cancer. We demonstrated the inhibitory effect of St. John’s Wort (SJW) on growth in the triple-negative breast cancer (TNBC) cell line and xenografted mice and...

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Bibliographic Details
Main Authors: Mikyoung You, Young-Hyun Lee, Hwa-Jin Kim, Ji Hyun Kook, Hyeon-A Kim
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nutrients
Subjects:
triple-negative breast cancer
autophagy
apoptosis
St. John’s Wort
Online Access:https://www.mdpi.com/2072-6643/12/10/3175

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