Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements

Essig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesti...

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Main Authors:	Jaclyn Essig, Joshua B. Hunt, Gidon Felsen
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-021-02248-1

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spelling	doaj-4d9635fae3884e5b8809b8c63d6020a32021-06-13T11:33:42ZengNature Publishing GroupCommunications Biology2399-36422021-06-014111410.1038/s42003-021-02248-1Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movementsJaclyn Essig0Joshua B. Hunt1Gidon Felsen2Department of Physiology and Biophysics, and Neuroscience Program University of Colorado School of MedicineDepartment of Physiology and Biophysics, and Neuroscience Program University of Colorado School of MedicineDepartment of Physiology and Biophysics, and Neuroscience Program University of Colorado School of MedicineEssig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesting that functional long-range inhibition instead plays a dominant role in spatial choice.https://doi.org/10.1038/s42003-021-02248-1
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Jaclyn Essig Joshua B. Hunt Gidon Felsen
spellingShingle	Jaclyn Essig Joshua B. Hunt Gidon Felsen Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements Communications Biology
author_facet	Jaclyn Essig Joshua B. Hunt Gidon Felsen
author_sort	Jaclyn Essig
title	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_short	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_full	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_fullStr	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_full_unstemmed	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_sort	inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
publisher	Nature Publishing Group
series	Communications Biology
issn	2399-3642
publishDate	2021-06-01
description	Essig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesting that functional long-range inhibition instead plays a dominant role in spatial choice.
url	https://doi.org/10.1038/s42003-021-02248-1
work_keys_str_mv	AT jaclynessig inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements AT joshuabhunt inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements AT gidonfelsen inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements
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Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements

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