Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide

Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide

An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities...

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Bibliographic Details
Main Authors: Dandan Xie, Ying Xie, Yan Ding, Jian Wu, Deyu Hu
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Molecules
Subjects:
chalcone derivatives
enantioselective catalysis
chiral cinchona alkaloid squaramides
addition reaction
Online Access:http://www.mdpi.com/1420-3049/19/12/19491
Description
Summary:An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities (up to 99%).
ISSN:1420-3049

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