Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVACResearch in context

Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVACResearch in context

Background: VAR2CSA is the lead antigen for developing a vaccine that would protect pregnant women against placental malaria. A multi-system feasibility study has identified E. coli as a suitable bacterial expression platform allowing the production of recombinant VAR2CSA-DBL1x-2x (PRIMVAC) to envis...

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Bibliographic Details
Main Authors:	Arnaud Chêne, Stéphane Gangnard, Anna Guadall, Hervé Ginisty, Odile Leroy, Nicolas Havelange, Nicola K. Viebig, Benoît Gamain
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Series:	EBioMedicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396419301501

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