Cocrystallization of gliclazide with improved physicochemical properties

Cocrystallization of gliclazide with improved physicochemical properties

Abstract Background Cocrystallization is one of the crystal engineering strategies used to alter the physicochemical properties of drugs that are poorly water-soluble. Gliclazide (GLZ), an antidiabetic drug, belongs to Biopharmaceutical Classification System class-II (low solubility and high permeab...

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Bibliographic Details
Main Authors: Shivarani Eesam, Jaswanth S. Bhandaru, Raghuram Rao Akkinepally, Ravi Kumar Bobbala
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Gliclazide
Cocrystallization
Solubility
In vitro dissolution
Bioavailability
Online Access:https://doi.org/10.1186/s43094-021-00261-z

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