Radiographic Assessment of Bone Formation Using rhBMP2 at Maxillary Periapical Surgical Defects: A Case Series
Periapical cysts are the most common inflammatory odontogenic cysts arising from untreated dental caries with pulp necrosis and periapical infection. The choice of treatment is often influenced by various factors like size, extension of the lesion, proximity to vital structures, systemic condition...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7522/11775_CE(RA1)_F(T)_PF1(BMAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Periapical cysts are the most common inflammatory odontogenic cysts arising from untreated dental caries with pulp necrosis and
periapical infection. The choice of treatment is often influenced by various factors like size, extension of the lesion, proximity to
vital structures, systemic condition and compliance of the patient too. The treatment protocol for management of periapical cysts
is still under discussion and options vary from conservative treatment by means of endodontic technique to surgical treatment like
decompression or a marsupialisation or even to enucleation. Large bony defect secondary to periapical surgery compromising the
tooth integrity often requires bone graft to enhance bone formation and thus restoring function at the earliest.
The present case series included 10 patients who had established periapical pathology secondary to history of trauma on upper anterior
teeth as well patients with history of carious teeth with an apparent failure in root canal therapy. All ten patients were treated with cyst
enucleation and apiceotomy along with 1.4cc Recombinant Human Bone Morphogenetic Protein-2 soaked Absorbable Collagen Sponge
implantation at surgical defect. Radiographs and clinical examinations were done upto 3 months to evaluate healing. Radiographic and
clinical assessments revealed bone regeneration and restoration of the maxillary surgical defects in all 10 patients. No evidence of graft
failure was noted. The Recombinant Human Bone Morphogenetic Protein-2 soaked Absorbable Collagen Sponge carrier is thus proved
to be a viable option for the treatment of maxillary periapical surgical defects. |
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| ISSN: | 2249-782X 0973-709X |