Synthesis and Evaluation of Antimicrobial and Cytotoxic Activity of Oxathiine-Fused Quinone-Thioglucoside Conjugates of Substituted 1,4-Naphthoquinones

Synthesis and Evaluation of Antimicrobial and Cytotoxic Activity of Oxathiine-Fused Quinone-Thioglucoside Conjugates of Substituted 1,4-Naphthoquinones

A series of new tetracyclic oxathiine-fused quinone-thioglycoside conjugates based on biologically active 1,4-naphthoquinones and 1-mercapto derivatives of per-<i>O</i>-acetyl d-glucose, d-galactose, d-xylose, and l-arabinose have been synthesized, characterized, and evaluated for their...

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Bibliographic Details
Main Authors: Yuri E. Sabutski, Ekaterina S. Menchinskaya, Ludmila S. Shevchenko, Ekaterina A. Chingizova, Artur R. Chingizov, Roman S. Popov, Vladimir A. Denisenko, Valery V. Mikhailov, Dmitry L. Aminin, Sergey G. Polonik
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
1,4-naphthoquinones
quinoid compounds
thioglycosides
quinone-sugar conjugates
cytotoxic activity
antibiotic activity
Online Access:https://www.mdpi.com/1420-3049/25/16/3577

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