Effects of Anti-Cytokine Antibodies on Gut Barrier Function

Effects of Anti-Cytokine Antibodies on Gut Barrier Function

Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re...

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Main Authors: Fang Liu, Seul A. Lee, Stephen M. Riordan, Li Zhang, Lixin Zhu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/7028253
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spelling doaj-4d8c2aefd0c446758223f867469acdef2020-11-25T01:57:42ZengHindawi LimitedMediators of Inflammation0962-93511466-18612019-01-01201910.1155/2019/70282537028253Effects of Anti-Cytokine Antibodies on Gut Barrier FunctionFang Liu0Seul A. Lee1Stephen M. Riordan2Li Zhang3Lixin Zhu4Department of General Surgery and Central Lab, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, AustraliaGastrointestinal and Liver Unit, Prince of Wales Hospital, University of New South Wales, Sydney, NSW, AustraliaSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, AustraliaDepartment of General Surgery and Central Lab, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaAnti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. This paper reviews the effects of anti-cytokine antibodies on gut barrier function and their mechanisms.http://dx.doi.org/10.1155/2019/7028253
collection DOAJ
language English
format Article
sources DOAJ
author Fang Liu
Seul A. Lee
Stephen M. Riordan
Li Zhang
Lixin Zhu
spellingShingle Fang Liu
Seul A. Lee
Stephen M. Riordan
Li Zhang
Lixin Zhu
Effects of Anti-Cytokine Antibodies on Gut Barrier Function
Mediators of Inflammation
author_facet Fang Liu
Seul A. Lee
Stephen M. Riordan
Li Zhang
Lixin Zhu
author_sort Fang Liu
title Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_short Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_full Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_fullStr Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_full_unstemmed Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_sort effects of anti-cytokine antibodies on gut barrier function
publisher Hindawi Limited
series Mediators of Inflammation
issn 0962-9351
1466-1861
publishDate 2019-01-01
description Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. This paper reviews the effects of anti-cytokine antibodies on gut barrier function and their mechanisms.
url http://dx.doi.org/10.1155/2019/7028253
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AT stephenmriordan effectsofanticytokineantibodiesongutbarrierfunction
AT lizhang effectsofanticytokineantibodiesongutbarrierfunction
AT lixinzhu effectsofanticytokineantibodiesongutbarrierfunction
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