Polymorphisms of Satellite DNA CYP19 Gene and its Association with Increased Risk of Breast Cancer in Isfahan, Iran

Polymorphisms of Satellite DNA CYP19 Gene and its Association with Increased Risk of Breast Cancer in Isfahan, Iran

Background: Aromatase is a key enzyme in the synthesis of estrogen. This enzyme is encoded by the cytochrome P-450 (CYP19) gene. Overexposure of cells to estrogen causes breast carcinoma and breast cancer patients show a higher level of aromatase expression. The purpose of this study was to investig...

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Bibliographic Details
Main Authors: Seyed Morteza Javadirad, Simin Hemati, Manochehr Tavassoli
Format: Article
Language:fas
Published: Vesnu Publications 2012-03-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Breast cancer
Microsatellite
Polymorphism
CYP19
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/1049

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