Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus

Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus

<p>Abstract</p> <p>Background</p> <p>Evc is essential for Indian Hedgehog (Hh) signalling in the cartilage growth plate. The gene encoding Evc2 is in close proximity in divergent orientation to <it>Evc </it>and mutations in both human genes lead to the chond...

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Bibliographic Details
Main Authors: Ponting Chris P, MacArthur Katie, Campbell Jennifer, Liu Yu-Ning, Tompson Stuart, Blair Helen J, Ruiz-Perez Victor L, Goodship Judith A
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/14

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