End-tagging of ultra-short antimicrobial peptides by W/F stretches to facilitate bacterial killing.

BACKGROUND: Due to increasing resistance development among bacteria, antimicrobial peptides (AMPs), are receiving increased attention. Ideally, AMP should display high bactericidal potency, but low toxicity against (human) eukaryotic cells. Additionally, short and proteolytically stable AMPs are des...

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Bibliographic Details
Main Authors: Mukesh Pasupuleti, Artur Schmidtchen, Anna Chalupka, Lovisa Ringstad, Martin Malmsten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2667214?pdf=render