Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions

Inhibition of action is involved in stopping a movement, as well as terminating unnecessary movement during performance of a behavior. The inhibition of single actions, known as response inhibition (Inhibition of the urge to respond before or after actions) has been widely investigated using the go/...

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Main Authors: Kei Omata, Shigeru Ito, Youhei Takata, Yasuomi Ouchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00951/full
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spelling doaj-4d7f17abcebc443390d30b837b58274c2020-11-24T21:10:27ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2018-12-011210.3389/fnins.2018.00951415968Similar Neural Correlates of Planning and Execution to Inhibit Continuing ActionsKei Omata0Shigeru Ito1Youhei Takata2Yasuomi Ouchi3Department of Biofunctional Imaging, Medical Photonics Research Center, Hamamatsu University School of Medicine, Hamamatsu, JapanHamamatsu Medical Photonics Foundation, Hamamatsu PET Imaging Center, Hamamatsu, JapanHamamatsu Photonics KK, Global Strategic Challenge Center, Hamamatsu, JapanDepartment of Biofunctional Imaging, Medical Photonics Research Center, Hamamatsu University School of Medicine, Hamamatsu, JapanInhibition of action is involved in stopping a movement, as well as terminating unnecessary movement during performance of a behavior. The inhibition of single actions, known as response inhibition (Inhibition of the urge to respond before or after actions) has been widely investigated using the go/no-go task and stop signal task. However, few studies focused on phase and volition-related inhibition after an action has been initiated. Here, we used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of planning and execution underlying the voluntary inhibition of ongoing action. We collected fMRI data while participants performed a continuous finger-tapping task involving voluntary and involuntary (externally directed) inhibition, and during the initiation of movement. The results revealed areas of significantly greater activation during the preparation of inhibition of an ongoing action during voluntary inhibition, compared with involuntary inhibition, in the supplementary (SMA) and pre-supplementary motor areas, dorsolateral prefrontal cortex, inferior frontal gyrus (IFG), inferior parietal lobe, bilateral globus pallidus/putamen, bilateral insula and premotor cortex. Focusing on the period of execution of inhibition of ongoing actions, an event-related fMRI analysis revealed significant activation in the SMA, middle cingulate cortex, bilateral insula, right IFG and inferior parietal cortex. Additional comparative analyses suggested that brain activation while participants were planning to inhibit an ongoing action was similar to that during planning to start an action, indicating that the same neural substrates of motor planning may be recruited even when an action is ongoing. The present finding that brain activation associated with inhibiting ongoing actions was compatible with that seen in response inhibition (urge to stop before/after actions) suggests that common inhibitory mechanisms for motor movement are involved in both actual and planned motor action, which makes our behavior keep going seamlessly.https://www.frontiersin.org/article/10.3389/fnins.2018.00951/fullbehavioral inhibitionsimple finger tappingvoluntary decisioncued judgmentneural substratesfunctional magnetic resonance imaging
collection DOAJ
language English
format Article
sources DOAJ
author Kei Omata
Shigeru Ito
Youhei Takata
Yasuomi Ouchi
spellingShingle Kei Omata
Shigeru Ito
Youhei Takata
Yasuomi Ouchi
Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
Frontiers in Neuroscience
behavioral inhibition
simple finger tapping
voluntary decision
cued judgment
neural substrates
functional magnetic resonance imaging
author_facet Kei Omata
Shigeru Ito
Youhei Takata
Yasuomi Ouchi
author_sort Kei Omata
title Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
title_short Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
title_full Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
title_fullStr Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
title_full_unstemmed Similar Neural Correlates of Planning and Execution to Inhibit Continuing Actions
title_sort similar neural correlates of planning and execution to inhibit continuing actions
publisher Frontiers Media S.A.
series Frontiers in Neuroscience
issn 1662-453X
publishDate 2018-12-01
description Inhibition of action is involved in stopping a movement, as well as terminating unnecessary movement during performance of a behavior. The inhibition of single actions, known as response inhibition (Inhibition of the urge to respond before or after actions) has been widely investigated using the go/no-go task and stop signal task. However, few studies focused on phase and volition-related inhibition after an action has been initiated. Here, we used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of planning and execution underlying the voluntary inhibition of ongoing action. We collected fMRI data while participants performed a continuous finger-tapping task involving voluntary and involuntary (externally directed) inhibition, and during the initiation of movement. The results revealed areas of significantly greater activation during the preparation of inhibition of an ongoing action during voluntary inhibition, compared with involuntary inhibition, in the supplementary (SMA) and pre-supplementary motor areas, dorsolateral prefrontal cortex, inferior frontal gyrus (IFG), inferior parietal lobe, bilateral globus pallidus/putamen, bilateral insula and premotor cortex. Focusing on the period of execution of inhibition of ongoing actions, an event-related fMRI analysis revealed significant activation in the SMA, middle cingulate cortex, bilateral insula, right IFG and inferior parietal cortex. Additional comparative analyses suggested that brain activation while participants were planning to inhibit an ongoing action was similar to that during planning to start an action, indicating that the same neural substrates of motor planning may be recruited even when an action is ongoing. The present finding that brain activation associated with inhibiting ongoing actions was compatible with that seen in response inhibition (urge to stop before/after actions) suggests that common inhibitory mechanisms for motor movement are involved in both actual and planned motor action, which makes our behavior keep going seamlessly.
topic behavioral inhibition
simple finger tapping
voluntary decision
cued judgment
neural substrates
functional magnetic resonance imaging
url https://www.frontiersin.org/article/10.3389/fnins.2018.00951/full
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