Budesonide suppresses pulmonary antibacterial host defense by down-regulating cathelicidin-related antimicrobial peptide in allergic inflammation mice and in lung epithelial cells

Budesonide suppresses pulmonary antibacterial host defense by down-regulating cathelicidin-related antimicrobial peptide in allergic inflammation mice and in lung epithelial cells

<p>Abstract</p> <p>Background</p> <p>Glucocorticoids are widely regarded as the most effective treatment for asthma. However, the direct impact of glucocorticoids on the innate immune system and antibacterial host defense during asthma remain unclear. Understanding the...

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Bibliographic Details
Main Authors: Wang Peng, Wang Xiaoyun, Yang Xiaoqiong, Liu Zhigang, Wu Min, Li Guoping
Format: Article
Language:English
Published: BMC 2013-02-01
Series:BMC Immunology
Subjects:
Allergic airway inflammation
Antibacterial host defense
Cathelicidin
Budesonide
Online Access:http://www.biomedcentral.com/1471-2172/14/7

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