Decreased Phosphorylated Protein Kinase B (Akt) in Individuals with Autism Associated with High Epidermal Growth Factor Receptor (EGFR) and Low Gamma-Aminobutyric Acid (GABA)

Dysregulation of the PI3K/AKT/ mammalian target of rapamycin (mTOR) pathway could contribute to the pathogenesis of autism spectrum disorders. In this study, phosphorylated Akt concentration was measured in 37 autistic children and 12, gender and age similar neurotypical, controls using an enzyme-li...

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Bibliographic Details
Main Author: Anthony J. Russo
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S21946

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