α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions
Abstract Background Keratinocytes form the main protective barrier in the skin to separate the underlying tissue from the external environment. In order to maintain this barrier, keratinocytes form robust junctions between neighbouring cells as well as with the underlying extracellular matrix. Cell–...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-021-01054-9 |