Functional Haplotypes in the Promoter Region of Transcription Factor Nrf2 in Chronic Obstructive Pulmonary Disease

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) protects against oxidative stress which is important in the pathogenesis of chronic obstructive pulmonary disease (COPD). Three single nucleotide polymorphisms and 1 triplet repeat polymorphism are found in the promoter region of the Nrf2 gene. Mole...

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Bibliographic Details
Main Authors: Chung-Ching Hua, Liang-Che Chang, Jo-Chi Tseng, Chien-Ming Chu, Yu-Chih Liu, Wen-Bin Shieh
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2010-0700