Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces

Abstract Background The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of antibiotic resistance genes as selection...

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Bibliographic Details
Main Authors: Laura Sevillano, Margarita Díaz, Ramón I. Santamaría
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0781-y