Apoptosis and autophagy in breast cancer cells following exemestane treatment.

Apoptosis and autophagy in breast cancer cells following exemestane treatment.

Aromatase inhibitors (AIs), which block the conversion of androgens to estrogens, are used for hormone-dependent breast cancer treatment. Exemestane, a steroidal that belongs to the third-generation of AIs, is a mechanism-based inhibitor that binds covalently and irreversibly, inactivating and desta...

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Bibliographic Details
Main Authors: Cristina Amaral, Margarida Borges, Soraia Melo, Elisiário Tavares da Silva, Georgina Correia-da-Silva, Natércia Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418278?pdf=render

Internet

http://europepmc.org/articles/PMC3418278?pdf=render

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