Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
Allergen-specific immunotherapy is used to treat patients affected by acute immunoglobulin E (IgE) responses, but the function mechanism is unclear. Here the authors show that the administration of two cat allergen-specific IgGs reduces allergic responses in mouse models and helps ameliorate clinica...
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Bibliographic Details
| Main Authors: |
J. M. Orengo,
A. R. Radin,
V. Kamat,
A. Badithe,
L. H. Ben,
B. L. Bennett,
S. Zhong,
D. Birchard,
A. Limnander,
A. Rafique,
J. Bautista,
A. Kostic,
D. Newell,
X. Duan,
M. C. Franklin,
W. Olson,
T. Huang,
N. A. Gandhi,
L. Lipsich,
N. Stahl,
N. J. Papadopoulos,
A. J. Murphy,
G. D. Yancopoulos |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-03636-8
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