Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation

Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation

Inappropriate inflammation exacerbates a vast array of chronic and acute conditions with severe health risks. In certain situations, such as acute sepsis, traditional therapies may be inadequate in preventing severe organ damage or death. We have previously shown cell surface glycan modification by...

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Bibliographic Details
Main Authors: Mehrab Nasirikenari, Amit A. Lugade, Sriram Neelamegham, Zhongwei Gao, Kelley W. Moremen, Paul N. Bogner, Yasmin Thanavala, Joseph T. Y. Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
sialylation
ST6Gal-1
inflammation
infection
airway
extrinsic glycosylation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00048/full

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