IATROGENIC RISK FACTORS OF CRITICAL STATES IN CHILDREN WITH INFECTIOUS PATHOLOGY

• Main Authors: A. N. Shmаkov, Yu. S. Аleksаndrovich, N. L. Elizаryevа, K. V. Pshenisnov, V. N. Kokhno
• Format: Article
• Language: Russian
• Published: NEW TERRA Publishing House 2018-05-01
• Series: Вестник анестезиологии и реаниматологии
• Subjects: sepsis; infectious diseases; children; odds ratio; outcome
• Online Access: https://www.vair-journal.com/jour/article/view/225
• ISSN: 2078-5658; 2541-8653

Critical states developed during infectious diseases are amongst main causes of lethal outcomes in children.The objective of the study: to find major signs of iatrogenic risk of critical states during infectious diseases in children.Subjects and methods. The examination protocols of 1 237 children in the age from 3 months to 15 years old were studied, all children had sepsis and were staying in central district hospitals and managed by doctors from emergency wards and planned care units from 2007 to 2011.Results of the study. The retrospective analysis proved the significance of the delayed start of intensive care for the risk of unfavorable outcome of gastrointestinal infections in children. The maximum permissible time of 45 minutes before the start of intensive care was substantiated. The risk factors of unfavorable outcome of gastrointestinal infections were defined for the period of treatment before the transfer to anesthesiology and intensive care wards: early prescription of intestinal antiseptics during in-take of antidiarrheal drugs (OR=4.0) and use of paracetamol and ibuprofen (OR=3.2).Conclusion: intensive care started as early as possible in children with infectious diseases and initiated within 15 minutes after the admission to intensive care ward is associated with the reduced risk of a lethal outcome.