Elevated expression of MMP8 and MMP9 contributes to diabetic osteoarthritis progression in a rat model
Abstract Background Knowledge regarding the pathogenesis of osteoarthritis (OA) is very limited. Previous studies have shown that matrix metalloproteinase (MMP) 8 and MMP9 were upregulated in patients with diabetic OA. However, their regulatory functions and mechanisms in diabetic OA are not fully u...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-021-02208-9 |