Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures

This study showed that Penicillium chrysogenum exhibits during submerged cultivation two distinct features: a filamentous structure characterized by long, branched, loose hyphae, and a pelletized morphological structure characterized by short, thickened hyphae clustered in a glomerule-like formation...

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Main Authors:	Ioan Leuca, Simona Dunca, Octavita Ailiesei
Format:	Article
Language:	English
Published:	"Alexandru Ioan Cuza" University of Iași 2008-05-01
Series:	Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:	http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/665

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spelling	doaj-4d04ecb9dc364d4ab8ac4dac3c1107292020-11-24T22:35:09Zeng"Alexandru Ioan Cuza" University of IașiAnalele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara 1582-35712248-32762008-05-0192658Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure culturesIoan LeucaSimona DuncaOctavita AilieseiThis study showed that Penicillium chrysogenum exhibits during submerged cultivation two distinct features: a filamentous structure characterized by long, branched, loose hyphae, and a pelletized morphological structure characterized by short, thickened hyphae clustered in a glomerule-like formation called pellet. With a view to maintaining the potential to biosynthesize the pelletized strain penicillin to a maximum, the operations involving the selection, multiplication and variability control of pure culture should be conducted periodically to prevent phenotypic and genotypic deviations to parental forms.http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/665
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ioan Leuca Simona Dunca Octavita Ailiesei
spellingShingle	Ioan Leuca Simona Dunca Octavita Ailiesei Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
author_facet	Ioan Leuca Simona Dunca Octavita Ailiesei
author_sort	Ioan Leuca
title	Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
title_short	Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
title_full	Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
title_fullStr	Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
title_full_unstemmed	Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
title_sort	stabilization of the penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures
publisher	"Alexandru Ioan Cuza" University of Iași
series	Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
issn	1582-3571 2248-3276
publishDate	2008-05-01
description	This study showed that Penicillium chrysogenum exhibits during submerged cultivation two distinct features: a filamentous structure characterized by long, branched, loose hyphae, and a pelletized morphological structure characterized by short, thickened hyphae clustered in a glomerule-like formation called pellet. With a view to maintaining the potential to biosynthesize the pelletized strain penicillin to a maximum, the operations involving the selection, multiplication and variability control of pure culture should be conducted periodically to prevent phenotypic and genotypic deviations to parental forms.
url	http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/665
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Stabilization of the Penicillium chrysogenum strain with pelletized morphological structure by selection, multiplication, and control of the variability of pure cultures

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