Comparison of the effects of olsalazine and decitabine on the expression of CDH1 and uPA genes and cytotoxicity in MDA-MB-231 breast cancer cells

Comparison of the effects of olsalazine and decitabine on the expression of CDH1 and uPA genes and cytotoxicity in MDA-MB-231 breast cancer cells

Background and purpose: Since DNA methyltransferase enzymes play a key role in DNA methylation, they can be used as a target to alter epigenetic changes and treat cancer. Recent studies have shown that olsalazine, through its potent inhibitory effect on the DNA methyltransferase enzyme, can be a goo...

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Bibliographic Details
Main Authors: Misagh Mohammadi Asl, Javad Mohammadi Asl, Mojgan Naghitorabi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
cancer; cdh1; decitabine; epigenetic; olsalazine; upa
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=3;spage=278;epage=285;aulast=Asl

Internet

http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=3;spage=278;epage=285;aulast=Asl

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