An unusual case of invasive papillary carcinoma of the breast

• Main Authors: Aysen Terzi, Aysegul Hasegeli Uner
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2012-01-01
• Series: Indian Journal of Pathology and Microbiology
• Subjects: High nuclear grade; invasive papillary carcinoma-breast; node negative; triple negative-breast cancer
• Online Access: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=543;epage=545;aulast=Terzi

Invasive papillary carcinoma is a rare variant of breast cancer. We report an unusual case of invasive papillary carcinoma of the breast with high nuclear grade, brisk mitosis, necrosis, extensive apocrine differentiation, and intense lymphoplasmacytic infiltrate; additionally triple-negativity for estrogen and progesterone receptors and Her2 neu. The patient underwent modified radical mastectomy and adjuvant chemotherapy. But, it was a node negative breast carcinoma. Increasing the awareness of this clinicopathologic entity would be helpful in avoiding overtreatment of patients with this cancer even if the tumor has negative morphological and immunohistochemical prognosticators.