Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth

Regulation of organ growth is a poorly understood process. In the long bones, the growth plates (GPs) drive elongation by generating a scaffold progressively replaced by bone. Although studies have focused on intrinsic GP regulation, classic and recent experiments suggest that local signals also mod...

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Bibliographic Details
Main Authors: Alberto Roselló-Díez, Daniel Stephen, Alexandra L Joyner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/27210