Function and Pathological Implications of Exon Junction Complex Factor Y14

Function and Pathological Implications of Exon Junction Complex Factor Y14

Eukaryotic mRNA biogenesis involves a series of interconnected steps, including nuclear pre-mRNA processing, mRNA export, and surveillance. The exon-junction complex (EJC) is deposited on newly spliced mRNAs and coordinates several downstream steps of mRNA biogenesis. The EJC core protein, Y14, func...

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Bibliographic Details
Main Authors: Tzu-Wei Chuang, Kou-Ming Lee, Woan-Yuh Tarn
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Biomolecules
Subjects:
exon-junction complex
nonsense-mediated mRNA decay
translation
pre-mRNA splicing
centrosome
Online Access:http://www.mdpi.com/2218-273X/5/2/343

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